The main aim of this study was to analyze the scientific productivity and collaboration between Old World wine-producing countries (Austria, Bulgaria, France, Germany, Greece, Hungary, Italy, Portugal, Romania, Spain, Switzerland) and New World wine-producing countries (Argentina, Australia, Brazil, Canada, Chile, Mexico, New Zealand, Peru, South Africa, United Sates, Uruguay) in viticulture and oenology through bibliometric analyses of articles included in the Science Citation Index Expanded database for the period 1994–2013. A number of 1527 research articles were published in 563 journals. The results highlight an important growth in the collaboration between countries during the second decade (2004–2013). Papers have been published in numerous journals belonging to several subject areas. Food Science and Technology, Horticulture and Biotechnology and Applied Microbiology appeared as the most productive research areas. A social network analysis of collaboration between these countries was also performed in order to analyze the most powerful scientific cooperation.